Publications

Joshua Cook (2022). Studying the Tissue Specificity of Cancer Driver Genes Through KRAS and Genetic Dependency Screens. Harvard University.

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Huynh, Minh V and Hobbs, G Aaron and Schaefer, Antje and Pierobon, Mariaelena and Carey, Leiah M and Diehl, J Nathaniel and DeLiberty, Jonathan M and Thurman, Ryan D and Cooke, Adelaide R and Goodwin, Craig M and Cook, Joshua H and Lin, Lin and Waters, Andrew M and Rashid, Naim U and Petricoin, 3rd, Emanuel F and Campbell, Sharon L and Haigis, Kevin M and Simeone, Diane M and Lyssiotis, Costas A and Cox, Adrienne D and Der, Channing J (2022). Functional and biological heterogeneity of KRAS Q61 mutations. Sci. Signal..

DOI PubMed Sci. Signal.

Joshua H. Cook, Giorgio E. M. Melloni, Doga C. Gulhan, Peter J. Park, Kevin M. Haigis (2021). The origins and genetic interactions of KRAS mutations are allele- and tissue-specific. Nat. Comm..

PDF Code Dataset DOI PubMed Nat. Comm.

Emily J. Poulin, Asim K. Bera, Jia Lu, Yi-Jang Lin, Samantha Dale Strasser, Joao A. Paulo, Tannie Q. Huang, Carolina Morales, Wei Yan, Joshua Cook, Jonathan A. Nowak, Douglas K. Brubaker, Brian A. Joughin, Christian W. Johnson, Rebecca A. DeStefanis, Phaedra C. Ghazi, Sudershan Gondi, Thomas E. Wales, Roxana E. Iacob, Lana Bogdanova, Jessica J. Gierut, Yina Li, John R. Engen, Pedro A. Perez-Mancera, Benjamin S. Braun, Steven P. Gygi, Douglas A. Lauffenburger, Kenneth D. Westover, Kevin M. Haigis (2019). Tissue-specific oncogenic activity of KRAS A146T. Cancer Discov..

PDF Code DOI PubMed Cancer Discov.

Joshua H. Cook, Norikyo Ueno, Melissa B. Lodoen (2018). Toxoplasma gondii disrupts $\beta1$-integrin signaling and focal adhesion formation during monocyte hypermotility. J Biol Chem..

PDF DOI PubMed JBC

Julien Maillard, Soyoung Park, Sophie Croizier, Charlotte Vanacker, Joshua H. Cook, Vincent Prevot, Maithe Tauber, Sebastien G. Bouret (2016). Loss of Magel2 impairs the development of hypothalamic Anorexigenic circuits. Hum Mol Genet..

PDF DOI PubMed Hum Mol Genet.